Gigliotti 1984 | 21/1984 | 9/32 | | 6.18 | 2.20 (1.19 to 4.06) |
Miller 1992 | 126/143 | 101/141 | | 49.31 | 1.23 (1.09 to 1.39) |
Rose 2005 | 123/163 | 107/163 | | 44.52 | 1.15 (1.00 to 1.32) |
Total (95% CI) | 340 | 336 | | 100.00 | 1.24 (1.05 to 1.45) |
|
Total events: 270 (treatment), 217 (control) |
Test for heterogeneity:χ2 = 4.33, degrees of freedom = 2 (P = 0.12), l2 = 53.8% |
Test for overall effect: Z = 2.61 (P = 0.009) |