PT  - JOURNAL ARTICLE
AU  - Liam G Glynn
AU  - Andrew W Murphy
AU  - Susan M Smith
AU  - Knut Schroeder
AU  - Tom Fahey
TI  - Self-monitoring and other non-pharmacological interventions to improve the management of hypertension in primary care: a systematic review
AID  - 10.3399/bjgp10X544113
DP  - 2010 Dec 01
TA  - British Journal of General Practice
PG  - e476--e488
VI  - 60
IP  - 581
4099  - http://bjgp.org/content/60/581/e476.short
4100  - http://bjgp.org/content/60/581/e476.full
SO  - Br J Gen Pract2010 Dec 01; 60
AB  - Background Patients with high blood pressure (hypertension) in the community frequently fail to meet treatment goals: a condition labelled as ‘uncontrolled’ hypertension. The optimal way to organise and deliver care to hypertensive patients has not been clearly identified.Aim To determine the effectiveness of interventions to improve control of blood pressure in patients with hypertension.Design of study Systematic review of randomised controlled trials.Setting Primary and ambulatory care.Method Interventions were categorised as following: self-monitoring; educational interventions directed to the patient; educational interventions directed to the health professional; health professional- (nurse or pharmacist) led care; organisational interventions that aimed to improve the delivery of care; and appointment reminder systems. Outcomes assessed were mean systolic and diastolic blood pressure, control of blood pressure and proportion of patients followed up at clinic.Results Seventy-two RCTs met the inclusion criteria. The trials showed a wide variety of methodological quality. Self-monitoring was associated with net reductions in systolic blood pressure (weighted mean difference [WMD] −2.5mmHg, 95%CI = −3.7 to −1.3 mmHg) and diastolic blood pressure (WMD −1.8mmHg, 95%CI = −2.4 to −1.2 mmHg). An organised system of regular review allied to vigorous antihypertensive drug therapy was shown to reduce blood pressure and all-cause mortality in a single large randomised controlled trial.Conclusion Antihypertensive drug therapy should be implemented by means of a vigorous stepped care approach when patients do not reach target blood pressure levels. Self-monitoring is a useful adjunct to care while reminder systems and nurse/pharmacist -led care require further evaluation.