RT Journal Article
SR Electronic
T1 Delayed antibiotic prescribing and associated antibiotic consumption in adults with acute cough
JF British Journal of General Practice
JO Br J Gen Pract
FD British Journal of General Practice
SP e639
OP e646
DO 10.3399/bjgp12X654614
VO 62
IS 602
A1 Nick A Francis
A1 David Gillespie
A1 Jacqueline Nuttall
A1 Kerenza Hood
A1 Paul Little
A1 Theo Verheij
A1 Herman Goossens
A1 Samuel Coenen
A1 Christopher C Butler
YR 2012
UL http://bjgp.org/content/62/602/e639.abstract
AB Background Delayed antibiotic prescribing is promoted as a strategy to reduce antibiotic consumption, but its use and its effect on antibiotic consumption in routine care is poorly described.Aim To quantify delayed antibiotic prescribing in adults presenting in primary care with acute cough/lower respiratory tract infection (LRTI), duration of advised delay, consumption of delayed antibiotics, and factors associated with consumption.Design and setting Prospective observational cohort in general practices in 14 primary care networks in 13 European countries.Method GPs recorded clinical features and antibiotic prescribing for adults presenting with an acute infective illness with cough as the dominant symptom. Patients recorded their consumption of antibiotics from any source during the 28-day follow up.Results Two hundred and ten (6.3%) of 3368 patients with usable consultation data were prescribed delayed antibiotics. The median recommended delay period was 3 days. Seventy-five (44.4%) of the 169 with consumption data consumed the antibiotic course and a further 18 (10.7%) took another antibiotic during the study period. 50 (29.6%) started their delayed course on the day of prescription. Clinician diagnosis of upper respiratory tract/viral infection and clinician’s perception of patient’s wanting antibiotics were associated with less consumption of the delayed prescription. Patient’s wanting antibiotics was associated with greater consumption.Conclusion Delayed antibiotic prescribing was used infrequently for adults presenting in general practice with acute cough/LRTI. When used, the effect on antibiotic consumption was less than found in most trials. There are opportunities for standardising the intervention and promoting wider uptake.