TY - JOUR T1 - Treatment intensification in type 2 diabetes mellitus and obesity JF - British Journal of General Practice JO - Br J Gen Pract SP - 182 LP - 182 DO - 10.3399/bjgp13X665152 VL - 63 IS - 609 AU - Agnieszka Zawiejska AU - Jane McAleese AU - Prasad Yemparala AU - Shahrad Taheri Y1 - 2013/04/01 UR - http://bjgp.org/content/63/609/182.1.abstract N2 - As Dr Pierce’s editorial points out, there is increasing evidence from bariatric surgery and intensive weight-loss approaches that it is possible to significantly improve type 2 diabetes (T2D) to the point of remission in some individuals.1 Thus, there is a need to rethink the current approach to diabetes management. Pursuing glycaemic control in T2D has resulted in treatment intensification, including insulin initiation. This approach, however, commonly results in weight gain. We describe two cases questioning the inevitability of beta-cell failure in T2D, and highlight the need for judicious treatment intensification.A 65-year-old female with … ER -