IgE mediated (usually evident within minutes) | Non-IgE mediated (may be several hours before they present) |
---|---|
Skin | |
Pruritus | Pruritus |
Erythema | Erythema |
Acute urticaria: localised or generalised | Atopic eczema |
Acute angioedema: most commonly lips, face, around eyes | |
Gastrointestinal system | |
Angioedema: lips, tongue, palate | Gastroesophageal reflux disease |
Oral pruritus | Loose or frequent stools |
Nausea | Blood and/or mucus in stools |
Colicky abdominal pain | Abdominal pain |
Vomiting | Infantile colic |
Diarrhoea | Food refusal or aversion |
Constipation | |
Perianal redness | |
Pallor and tiredness | |
Faltering growth: in conjunction with at least ≥1 of the above gastrointestinal symptoms (with or without significant atopic eczema) | |
Respiratory system (usually in combination with ≥1 of the above symptoms and signs) | |
Upper respiratory tract symptoms: nasal itching, sneezing, rhinorrhoea, or congestion (with or without conjunctivitis) | |
Lower respiratory tract symptoms: cough, chest tightness, wheezing, or shortness of breath | |
Other | |
Signs or symptoms of anaphylaxis or other systemic allergic reactions |
↵a This list is not exhaustive. The absence of these symptoms does not exclude food allergy.