Derivation cohort, n (%) | Validation cohort, n (%) | |
---|---|---|
Red flag symptom | ||
Abdominal distension | 2340 (0.2) | 1145 (0.2) |
Abdominal pain | 91 476 (7.2) | 47 032 (6.9) |
Appetite loss | 4234 (0.3) | 1887 (0.3) |
Dysphagia | 7088 (0.6) | 3553 (0.5) |
Haematemesis | 7380 (0.6) | 3803 (0.6) |
Haematuria | 26 230 (2.1) | 13 527 (2.0) |
Haemoptysis | 7065 (0.6) | 3559 (0.5) |
Haematospermia | 2848 (0.2) | 1441 (0.2) |
Heartburn | 8846 (0.7) | 4388 (0.6) |
Indigestion | 42 367 (3.4) | 21 893 (3.2) |
Neck lump | 3758 (0.3) | 1967 (0.3) |
Night sweats | 2264 (0.2) | 1164 (0.2) |
Rectal bleeding | 27 446 (2.2) | 14 006 (2.1) |
Testicular pain | 5571 (0.4) | 2809 (0.4) |
Testicular lump | 8709 (0.7) | 4329 (0.6) |
Venous thrombo-embolism | 9073 (0.7) | 4603 (0.7) |
Weight loss | 11 197 (0.9) | 5860 (0.9) |
Recent general symptoms | ||
Back pain | 41 216 (3.3) | 21 725 (3.2) |
Bruising | 975 (0.1) | 470 (0.1) |
Change in bowel habit | 2614 (0.2) | 1321 (0.2) |
Constipation | 10 892 (0.9) | 5638 (0.8) |
Cough | 37 745 (3.0) | 19 338 (2.8) |
Diarrhoea | 17 936 (1.4) | 9073 (1.3) |
Dyspnoea | 9898 (0.8) | 4780 (0.7) |
Fever | 3830 (0.3) | 1741 (0.3) |
Headache | 14 844 (1.2) | 7882 (1.2) |
Hesitancy | 509 (0.0) | 236 (0.0) |
Impotence | 12 299 (1.0) | 6353 (0.9) |
Itching | 2066 (0.2) | 1122 (0.2) |
Nausea | 3762 (0.3) | 1636 (0.2) |
Nocturia | 3287 (0.3) | 1806 (0.3) |
Poor stream | 357 (0.0) | 188 (0.0) |
Tiredness | 12 370 (1.0) | 6132 (0.9) |
Urgency | 1109 (0.1) | 526 (0.1) |
Urinary dribbling | 457 (0.0) | 230 (0.0) |
Urinary frequency | 5147 (0.4) | 2638 (0.4) |
Urinary incontinence | 2141 (0.2) | 1033 (0.2) |
Urinary retention | 3113 (0.2) | 1594 (0.2) |