Top 10% of risk | Risk threshold % | True negative | False negative | False positive | True positive | Sensitivity % | Specificity, % | PPV, % | NPV, % |
---|---|---|---|---|---|---|---|---|---|
Lung cancer | 0.38 | 600 534 | 309 | 65 962 | 798 | 72.1 | 90.1 | 1.2 | 99.9 |
Colorectal cancer | 0.35 | 600 412 | 431 | 65 835 | 925 | 68.2 | 90.1 | 1.4 | 99.9 |
Gastro-oesophageal cancer | 0.14 | 600 705 | 138 | 66 347 | 413 | 75.0 | 90.1 | 0.6 | 100.0 |
Pancreas cancer | 0.12 | 600 721 | 122 | 66 502 | 258 | 67.9 | 90.0 | 0.4 | 100.0 |
Ovarian cancer | 0.18 | 600 610 | 233 | 66 387 | 373 | 61.6 | 90.0 | 0.6 | 100.0 |
Renal cancer | 0.1 | 600 727 | 116 | 66 378 | 382 | 76.7 | 90.0 | 0.6 | 100.0 |
Breast cancer | 0.72 | 599 414 | 1,429 | 63 710 | 3,050 | 68.1 | 90.4 | 4.6 | 99.8 |
Blood cancer | 0.22 | 600 449 | 394 | 66 451 | 309 | 44.0 | 90.0 | 0.5 | 99.9 |
Uterine cancer | 0.1 | 600 758 | 85 | 66 322 | 438 | 83.7 | 90.1 | 0.7 | 100.0 |
Cervical cancer | 0.05 | 600 742 | 101 | 66 639 | 121 | 54.5 | 90.0 | 0.2 | 100.0 |
Other cancer | 0.55 | 600 590 | 253 | 66 699 | 61 | 19.4 | 90.0 | 0.1 | 100.0 |
NPV = negative predictive value. PPV = positive predictive value.