Table 2

Diagnostic strategy in patients with stable chronic chest pain of suspected cardiac origin.

Prior probability of coronary artery diseaseInvestigative strategy and rationale
<10% (and/or non-anginal chest pain)Trust your clinical judgement: no further testing for CAD
10-30%Rule-out test needed: CT calcium +/− CT angiography
30-60%Uncertainty: non-invasive functional imaging
61-90%Rule-in test needed: invasive coronary angiography
>90% (with typical angina)Trust your clinical judgement: no further diagnostic testing