Adverse events experienced by participants
| Adverse event n(%) | Baselinea | Week 3b | 6 monthsc | |||
|---|---|---|---|---|---|---|
| Sleep restriction n= 46 | Control n= 51 | Sleep restriction n= 45 | Control n= 51 | Sleep restriction n= 43 | Control n= 48 | |
| Motor vehicle accident | 3 (7) | 4 (8) | 0 | 1 (2) | 2 (5) | 5 (10) |
| Injury | ||||||
| Medical attention | 9 (20) | 5 (10) | 0 | 1 (2) | 4 (9) | 6 (13) |
| No medical attention | 7 (15) | 5 (10) | 0 | 2 (4) | 2 (5) | 8 (17) |
| Worsening angina | 0 | 0 | 0 | 1 (2) | 0 | 0 |
| Myocardial infarction | 0 | 0 | 0 | 0 | 0 | 0 |
| Stroke | 0 | 0 | 0 | 0 | 0 | 0 |
| Hospitalisation | 3d(7) | 1e(2) | 0 | 0 | 3f(7) | 3g(6) |
| Sleepiness | ||||||
| Driving | 1(2) | 3 (6) | 1 (2) | 0 | 0 | 2 (4) |
| Childcare | 0 | 3 (6) | 1 (2) | 0 | 0 | 0 |
↵a Baseline questionnaire asks about occurrence of adverse events over preceding 6 months.
↵b Week-3 questionnaire asks about sleepiness in the preceding 2 weeks (that is, from time of treatment initiation).
↵c 6-month questionnaires asks about sleepiness in the preceding 6 months (that is, the duration of the trial).
↵d Panic attack, faint, pacemaker insertion.
↵e MRI, deafness, and loss of balance.
↵f Finger surgery, knee replacement, gallstones.
↵g Broken arm, ankle surgery, pneumonia.