Cost effectiveness of amoxicillin versus placeboa
| Cost effectiveness excluding the cost of antimicrobial resistance | |
| Difference in costs between amoxicillin and placebo groups, € (95% CI) | 3.04 (−1.36 to 7.44) |
| Difference in QALYs gained (95% CI) | 0.00037 (−0.0002 to 0.0009) |
| ICER, € | 8216 per QALY gained |
| Cost effectiveness including cost of resistance (US data) | |
| Difference in costs between amoxicillin and placebo groups, € (95% CI) | 81.47 (75.45 to 87.49) |
| Difference in QALYs gained (95% CI) | 0.00037 (−0.0002 to 0.0009) |
| ICER, € | 220 189 per QALY gained |
| Cost effectiveness including cost of resistance (EU data) | |
| Difference in costs between amoxicillin and placebo groups, € (95% CI) | 5.45 (1.06 to 9.85) |
| Difference in QALYs gained (95% CI) | 0.00037 (−0.0002 to 0.0009) |
| ICER, € | 14 730 per QALY gained |
| Cost effectiveness including cost of resistance (global data) | |
| Difference in costs between amoxicillin and placebo groups, € (95% CI) | 269.04 (251.87 to 286.22) |
| Difference in QALYs gained (95% CI) | 0.00037 (−0.0002 to 0.0009) |
| ICER, € | 727 135 per QALY gained |
↵a Figures obtained from the regression analysis/hierarchical model.
ICER = incremental cost-effectiveness ratio. QALY = quality-adjusted life year.