Table 1.

Cost of amoxicillin versus placebo, and associated health outcomes (mean [SD])a

CostsIntervention, € (n= 1037)Control, € (n= 1023)Difference, € (95% CI)b
Staff27.55 (43.11)26.88 (41.43)0.67 (−3.18 to 4.43)
Prescribed drug6.77 (13.10)5.95 (11.07)0.82 (−0.36 to 1.81)
Over-the-counter drug2.28 (6.16)2.46 (7.06)−0.18 (−0.72 to 0.40)
Intervention/other drug6.66 (12.48)7.75 (14.02)−1.09 (−2.19 to 0.10)
Other health care1.22 (13.29)1.76 (22.05)−0.54 (−2.32 to 0.79)
Intervention (amoxicillin)2.75 (2.45)02.75 (2.61 to 2.91)
Total (excluding resistance)47.23 (50.59)44.80 (54.84)2.43 (−2.19 to 6.53)
Health outcomes (EQ-5D-3L)
EQ-5D-3L baseline0.760 (0.185)0.752 (0.192)0.008 (−0.007 to 0.024)
EQ-5D-3L week 10.840 (0.173)0.824 (0.176)0.016 (0.002 to 0.033)
EQ-5D-3L week 20.908 (0.134)0.900 (0.134)0.008 (−0.004 to 0.018)
EQ-5D-3L week 30.929 (0.122)0.925 (0.122)0.004 (−0.006 to 0.015)
EQ-5D-3L week 40.936 (0.107)0.936 (0.109)0.0001 (−0.010 to 0.008)
  • a Figures represent the unadjusted difference in costs

  • b Bootstrapped CI.

  • EQ-5D-3L = three-level version of EQ-5D questionnaire. SD = standard deviation.