Table 2.

Summary of outcomes by exposure to the intervention, with adjusted and unadjusted intervention effects

Unexposed armExposed armPercentage difference (95% CI for primary outcomes and 99% CI for secondary outcomes)
UnadjustedaTime adjustedb
Persons (person years)2969 (1939.33)2926 (1795.48)
Treatment initiation, n(%)
  Antihypertensives or statins321 (10.8)577 (19.7)9.7 (7.9 to 11.4) P<0.00115.5 (3.9 to 27.1) P= 0.009
  Antihypertensives222 (7.5)333 (11.4)4.7 (3.4 to 6.1) P<0.0017.7 (−0.1 to 15.5) P= 0.054
  Statins188 (6.3)405 (13.8)7.7 (6.2 to 9.2) P<0.0019.5 (3.0 to 16.0) P= 0.004
  Antiplatelet agents or over-the-counter aspirin235 (7.9)263 (9.0)2.5 (1.8 to 3.2) P<0.0012.5 (−1.6 to 6.7) P= 0.230
Measurement of CVD risk factors, n(%)
  Patients with BP assessed825 (27.8)1285 (43.9)17.2 (14.3 to 20.0) P<0.00128.8 (−3.5 to 59.1) P= 0.022
  Patients with lipids assessed437 (14.7)1046 (35.7)21.1 (18.4 to 23.9) P<0.00126.4 (5.3 to 47.5) P= 0.001
Cardiovascular events, n(%)
  CVD events27 (0.91)17 (0.58)0.1 (−0.3 to 0.6) P= 0.4860.3 (−1.6 to 2.2) P= 0.685
Referrals, n(%)
  Referral to smoking cessation12 (0.40)30 (1.03)0.6 (0.1 to 1.2) P= 0.0023.3 (0.8 to 5.9) P= 0.001
  Referral to diet or physical activity advice4 (0.13)5 (0.17)0.0 (−0.2 to 0.3) P= 0.730−0.6 (−1.5 to 0.2) P= 0.055

  • ↵a The unadjusted model is adjusted for clustering.

  • ↵b The time-adjusted model is adjusted for the effect of time, clustering, and practice priority.

  • BP = blood pressure. CVD = cardiovascular disease.