Table 1.

Information on included studies, risk of bias and PEDro Score

StudySample sizeDropoutsIntervention designPrimary outcome measureSecondary outcome measure(s)Follow-up durationControlRisk of biasPEDro score
Allen et al 27Intervention (I) 190;
Control (C) 190
I: 25
C: 36
Comprehensive post-discharge care management intervention; assessment by nurse in participant’s home; reviewed by the treating medical team. Patient care plans developed. Periodic telephone calls to assess changeNone statedNeuromotor function (measured using NIHSS, Timed Up and Go test, and physical performance test); institution time (days spent hospitalised or in a nursing home during 6-month follow-up); death; quality of life (stroke-specific QOL scale); systolic and diastolic blood pressure (mmHg), depression (CES-D scale), medication appropriateness (an investigator generated tool), haemoglobin A1c (%), total cholesterol (mg/dL), self-reported falls and incontinence; stroke knowledge and lifestyle modification (an investigator-generated questionnaire that assesses knowledge of stroke risk factors and health behaviours)6 monthsUsual post-discharge care planningLow9
Tanne et al 30I: 43
C: 9
I: 2
C: 2
Education on vascular risk, physical exercise and healthy lifestyle; supervised exercise programme, twice/week for 3 months (15 minutes warm-up, 45 minutes on treadmill, stair machine and bicycle at 60–70% of maximal heart rate); prescribed by physiologist; supervised by physical therapy and cardiac rehabilitation staff. Exercise prescription adjusted if capacity improvedPhysical fitness — maximal exercise test, 6-minute walk test (metres walked)Resting heart rate (BPM) and resting systolic blood pressure (mmHg)3 monthsUsual post-TIA/stroke careHigh. Pilot non-random trial6
Toledano-Zarhi et al 28I:14
C: 14
I: 1
C: 0
Exercise group enrolled in 6-week supervised exercise programme (3 hours weekly: 2 sessions of 35–55 minutes on treadmill, hand-bike, and bicycle, supervised by physical therapy and cardiac rehabilitation staff: 8 progressive stages; also, 45–55 minutes group practice for strength, flexibility, and coordination Exercise prescription adjusted if capacity improvedExercise capacity — maximal exercise test, 6-minute walk test (metres walked)Adverse events (for example strokes or falls)6 weeksHome-exercise booklet, advising strength and flexibility exercises, plus normal routineUncertain7
Boysen et al 29I: 157
C: 157
I: 24
C: 14
Repeated encouragement and verbal instruction on being physically active given by a physiotherapist or neurologistPhysical activity assessed with the Physical Activity Scale for the ElderlyClinical events, for example number of strokes, or hospitalisations2 yearsVerbal information on benefits of physical activityLow risk9
  • BPM = beats per minute. CES-D = Center for Epidemiologic Studies - Depression. NIHSS = National Institutes of Health Stroke Scale. PEDro = Physiotherapy Evidence Database. QOL = quality of life. TIA = transient ischaemic attack.