Table 2.

NHS Forth Valley segmented regression analysis

Prescribing measuresBaseline rate, patients prescribed per 1000 at risk (95% CI)Pre-intervention period trend, change in rate per quarter (95% CI)Immediate step change in rate at start of intervention period (95% CI)Change in trend after start of intervention period, change in rate per quarter (95% CI)Immediate step change in rate at end of intervention period (95% CI)Change in trend after end of intervention period, change in rate per quarter (95% CI)Absolute difference at end of intervention period, patients prescribed per 1000 at risk (95% CI)Absolute difference 12 months post end of intervention period, patients prescribed per 100 00 at risk (95% CI)
2013–2014 outcome measures
‘Triple whammy’: patients aged ≥65 years prescribed NSAID + ACE/ARB + diuretica13.1 (12.4 to 13.8)−0.2 (−0.2 to −0.1)−0.5 (−1.3 to 0.3)−1.2 (−1.4 to −1.1)1.5 (1.1 to 1.9)1.3 (1.2 to 1.3)−5.5 (−6.7 to −4.3)−4.0 (−5.4 to −2.6)
NSAIDs in older people: patients aged ≥65 years prescribed NSAID without gastroprotectiona44.1 (42.9 to 45.4)−0.7 (−0.9 to −0.6)−1.6 (−3.8 to 0.6)−4.6 (−4.95 to −4.3)7.4 (6.2 to 8.5)5.2 (4.9 to 5.6)−20.1 (−23.0 to −17.1)−10.3 (−13.9 to −6.8)
NSAIDs with OAC: patients prescribed OAC + NSAID without gastroprotectionb9.1 (8.1 to 10.1)−0.2 (−0.3 to −0.04)−2.0 (−3.6 to −0.3)−0.3 (−0.8 to 0.2)0.6 (−0.8 to 2.0)0.6 (0.1 to 1.1)−3.3 (−4.9 to −1.6)−1.5 (−3.5 to 0.6)
2014–2015 outcome measure
Antipsychotics in older people: patients aged ≥75 years prescribed oral antipsychoticc19.6 (18.7 to 20.5)0.1 (−0.01 to 0.1)−0.1 (−1.1 to 0.8)0.1 (−0.1 to 0.3)−0.6 (−1.4 to 0.2)0.3 (0.1 to 0.6)0.2 (−1.2 to 1.5)1.2 (−0.5 to 2.9)
  • a Rate per 1000 population aged65 years.

  • b Rate per 1000 prescribed OAC.

  • c Rate per 1000 population aged75 years. ACE = angiotensin converting enzyme. ARB = angiotensin receptor blocker. NSAID = non-steroidal anti-inflammatory drug. OAC = oral anticoagulant.