Table 2.

Symptom severity on day 2–4 according to antibiotic prescription strategy

Antibiotic prescribing strategySymptom severity, mean (SD)Difference (95% CI), P-valueDifference controlling for clustering and, antibiotic type and baseline severity score (95% CI), P-valueDifference controlling for propensity score (95% CI), P-valueDifference controlling for propensity score in the imputed dataset (95% CI), P-value
None (reference)
n= 585
2.13 (1.24)
Immediate
n= 723
2.03 (1.20)−0.10 (−0.23 to 0.03), P = 0.140−0.30 (−0.49 to −0.21), P = 0.001−0.22 (0.44 to −0.01), P = 0.040−0.22 (−0.43 to −0.01), P = 0.043
Delayed
n= 196
1.95 (1.19)−0.17 (−0.37 to 0.02), P = 0.834−0.22 (−0.42 to −0.02), P = 0.034−0.26 (−0.45 to −0.7), P = 0.009−0.26 (−0.45 to −0.07), P = 0.008
  • SD = standard deviation.