Antibiotic prescribing strategy | Duration of moderately bad symptoms: median days (IQR) | Univariate hazard ratio, (95% CI), P-value | Hazard ratio controlling for clustering and baseline severity score (95% CI), P-value | Hazard ratio controlling for propensity score (95% CI), P-value | Hazard ratio controlling for propensity score in imputed dataset (95% CI), P-value |
---|---|---|---|---|---|

No Antibiotic (reference)n= 587 | 4 (2–7) | 1.00 | 1.00 | 1.00 | 1.00 |

Immediaten= 728 | 3 (2–5) | 1.33 (1.18 to 1.50), P<0.001 | 1.37 (1.23 to 1.53), P<0.001 | 1.21 (1.07 to 1.38), P = 0.004 | 1.20 (1.07 to 1.3), P = 0.002 |

Delayedn= 197 | 3 (2–6) | 1.15 (0.96 to 1.37), P = 0.120 | 1.16 (0.98 to 1.37), P = 0.084 | 1.10 (0.92 to 1.33), P = 0.300 | 1.10 (0.91 to 1.33), P = 0.316 |

*IQR = interquartile range.*