Reclassification of patients’ CKD stage when moving from a single test to the second of two eGFR measuresa
| CKD stage at first test | MDRD equation, n= 311 | CKD-EPI equation, n= 301 | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| First, eGFR n= 311, n | CKD stage at follow-up eGFR | First eGFR, n= 301, n (%) | CKD stage at follow-up eGFR | |||||||||
| Normal urinary ACR, n= 121, n (%) | Stage 1, n= 14, n (%) | Stage 2, n= 85, n (%) | Stage 3A, n= 77, n (%) | Stage 3B, n= 14, n (%) | Normal urinary ACR, n= 119, n (%) | Stage 1, n= 4, n (%) | Stage 2, n= 91, n (%) | Stage 3A, n= 72, n (%) | Stage 3B, n= 15, n (%) | |||
| Stage 1 | 41 | 25 (61) | 10b (24) | 6 (15) | 0 (0) | 0 (0) | 19 | 12 (63) | 4b (21) | 3 (16) | 0 (0) | 0 (0) |
| Stage 2 | 142 | 56 (39) | 4 (3) | 70b (49) | 11 (8) | 1 (0) | 166 | 71 (43) | 0 (0) | 83b (50) | 11 (7) | 1 (0) |
| Stage 3A | 115 | 39 (34) | 0 (0) | 9 (8) | 63b (55) | 4 (3) | 102 | 35 (34) | 0 (0) | 5 (5) | 58b (57) | 4 (4) |
| Stage 3B | 13 | 1 (7) | 0 (0) | 0 (0) | 3 (23) | 9b (69) | 13c | 1 (8) | 0 (0) | 0 (0) | 3 (23) | 9b (69) |
↵a Percentages are presented across rows representing those reclassified after the second measure for each stage of CKD, and separately for MDRD and CKD-EPI.
↵b Numbers of patients for whom the CKD stage did not change.
↵c One patient was Stage 4 at the first test and stage 3B (100%) after the second test. ACR = albumin:creatinine ratio. CKD = chronic kidney disease. CKD-EPI = Chronic Kidney Disease Epidemiology Collaboration. eGFR = estimated glomerular filtration rate. MDRD = Modification of Diet in Renal Disease.