Logistic regression of factors associated with referral from pharmacy to general practice for 131 419 patients
| n (%) | Referred n (%) | Adjusted OR (95% CI) | |
|---|---|---|---|
| Outcome variable | |||
| Referrals from pharmacy to general practice | 5895 (4.5) | – | – |
| Predictor variables | |||
| Patient-reported factors | |||
| Side effects | 24 992 (19.0) | 4155 (16.6) | 11.60 (10.85 to 12.41) |
| Not using the medicine as prescribed | 5271 (4.0) | 2236 (42.4) | 5.83 (5.23 to 6.52) |
| Negative feelings towards new BP medication | 5038 (3.8) | 1292 (25.6) | 3.29 (3.01 to 3.60) |
| Uncertainty whether medicine working | 8344 (6) | 555 (6.7) | 1.50 (1.35 to 1.68) |
| Not yet started the medication | 823 (0.6) | 230 (27.9) | 1.23 (1.02 to 1.50) |
| Concerns with remembering to take medication | 965 (0.7) | 60 (6.2) | 0.91 (0.68 to 1.24) |
| Difficulty with medication formulation | 149 (0.1) | 13 (8.7) | 0.81 (0.41 to 1.60) |
| Prescriber stopping the medication | 777 (0.6) | 313 (40.3) | 0.75 (0.62 to 0.91) |
| More information about medication needed | 7276 (5.5) | 301 (4.1) | 0.45 (0.39 to 0.52) |
| Missed dose in the past 7 days | 1166 (0.9) | 415 (35.6) | 0.42 (0.36 to 0.50) |
| Using medicine as prescribed | 107 989 (82.2) | 2354 (2.2) | 0.20 (0.18 to 0.21) |
| Demographic factors | |||
| Age, years (<40 years as reference) | |||
| 40–49 | 12 987 (9.9) | 463 (3.6) | 0.77 (0.63 to 0.93) |
| 50–59 | 23 451 (17.8) | 951 (4.1) | 0.89 (0.75 to 1.06) |
| 60–69 | 37 312 (28.4) | 1548 (4.1) | 0.87 (0.74 to 1.03) |
| 70–79 | 34 895 (26.6) | 1680 (4.8) | 0.93 (0.78 to 1.10) |
| ≥ 80 | 17 975 (13.8) | 1045 (5.8) | 1.05 (0.88 to 1.25) |
| Ethnicity (white as reference) | |||
| South Asian | 4586 (3.5) | 227 (4.9) | 1.14 (0.97 to 1.35) |
| Other | 1645 (1.3) | 91 (5.5) | 1.25 (0.97 to 1.62) |
| Not stated | 10 234 (7.8) | 476 (4.7) | 1.12 (1.00 to 1.26) |
| Black/African-Caribbean | 2760 (2.1) | 127 (4.6) | 0.94 (0.75 to 1.17) |
| Sex, male (female as reference) | 61 146 (46.5) | 2172 (3.6) | 0.85 (0.80 to 0.91) |
| Medication-related factors (CCB as reference) | |||
| Alpha-blocker | 5264 (4.0) | 411 (7.8) | 1.28 (1.12 to 1.47) |
| Beta-blocker | 16 211 (12.3) | 777 (4.8) | 1.10 (0.99 to 1.21) |
| Thiazide | 15 487 (11.8) | 800 (5.2) | 1.02 (0.92 to 1.13) |
| ACEi | 34 497 (26.2) | 1312 (3.8) | 0.94 (0.86 to 1.02) |
| ARB | 17 415 (13.3) | 622 (3.6) | 0.89 (0.80 to 0.99) |
| Other | 1173 (0.9) | 53 (4.5) | 0.77 (0.56 to 1.06) |
ACEi = angiotensin-converting enzyme inhibitor. ARB = angiotensin II receptor blocker. BP = blood pressure. CCB = calcium channel blocker. OR = odds ratio.