Elsevier

Preventive Medicine

Volume 8, Issue 1, January 1979, Pages 2-13
Preventive Medicine

General article
Therapeutic control of blood pressure in the hypertension detection and follow-up program,☆☆

https://doi.org/10.1016/0091-7435(79)90024-0Get rights and content

Abstract

To determine the effectiveness of antihypertensive therapy in reducing morbidity and mortality from hypertension in the general population, the Hypertension Detection and Follow-up Program is studying 11,237 hypertensives aged 30 to 69 years in 14 U.S. communities. Half were assigned randomly to Program clinics (Stepped Care) and half to their usual sources of care (Referred Care). The Program will follow both groups for 5 years. After 1 year, 80.4% of the participants receiving Stepped Care remained in active therapy, and 76.9% of these attained specified blood pressure goals: 39% with diuretics alone and 24% with diuretics plus single antiadrenergic agents. Diastolic blood pressure decrements over the year for mild, moderate, and severe hypertensives were 13.4, 22.3, and 33.8 mm Hg, respectively, and were greater in the Stepped Care group than in the Referred Care group. These rates of participation and blood pressure control achieved with simple therapy plus vigorous follow-up have encouraging implications for community programs and for clinicians.

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The research upon which this publication is based was performed pursuant to Contracts N01-HV-124 (33–42), N01-HV-229 (31, 37, 38, 39, 45), and N01-HV-32933, with the National Heart, Lung, and Blood Institute, NIH, Department of Health, Education and Welfare.

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Requests for reprints should be addressed to: Scientific Project Officer, Hypertension Detection and Follow-up Program, DHVD, National Heart, Lung and Blood Institute, NIH, Federal Building, Room 404, 7550 Wisconsin Avenue, Bethesda, Md. 20014.

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Members of the Writing Committee: M. Donald Blaufox, M.D., Ph.D.; David Curb, M.D.; Alex Kralios, M.D.; B. Frank Polk, M.D., M.Sc. (Chairperson); and Myra Tyler, M.D.

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