OBJECTIVES: The nature of public health evidence presents challenges for conventional
systematic review processes, with increasing recognition of the need to include a broader …

This review of interventions to promote mental well-being in primary school children concluded
that there is good evidence to support the implementation of programmes that include a …

This report is a systematic review of the published literature on the effectiveness of school
based interventions that aim to promote mental wellbeing amongst children in primary …

Objectives: We aimed to describe the clinical phenotype conferred by the intermediate-length
huntingtin allele CAG repeat expansion in a population-based study. Methods: The …

Participants with the gene expansion for Huntington disease (HD) but not yet diagnosed were
evaluated annually. Unidimensional diagnosis (UD) was a motor diagnosis defined as a …

BACKGROUND: There is increasing research supporting the argument for a beneficial link
between physical activity and health maintenance and, in the past five years, this has led to a …

BACKGROUND: By permitting remote assessments of patients and research participants,
telemedicine has the potential to reshape clinical care and clinical trials for Parkinson disease. …

This paper outlines the National Institute for Health and Clinical Excellence's (NICE) emerging
conceptual framework for public health. This is based on the experience of the first 3 …

Therapeutic decision‐making in Huntington's disease (HD) is often guided by clinical
experience, because of the limited empirical evidence available. The only medication for HD that …

Disulfide oxidoreductases are viewed as foldases that help to maintain proteins on
productive folding pathways by enhancing the rate of protein folding through the catalytic …