Background Vitamin D was used to treat tuberculosis in the pre-antibiotic era, and its
metabolites induce antimycobacterial immunity in vitro. Clinical trials investigating the effect of …

Background Most clinicians have no training about domestic violence, fail to identify patients
experiencing abuse, and are uncertain about management after disclosure. We tested the …

… cost function T = n C c 1 + C c 2 ⁠, where C is the total number of clusters, n the cluster size,
c 1 the costs per individual and c 2 the costs per cluster. The number of clusters, C, and the …

Objectives To assess the quality of reporting and accuracy of a priori estimates used in
sample size calculations for cluster randomized trials (CRTs). Study Design and Setting We …

Background Domestic violence affects one in four women and has significant health
consequences. Women experiencing abuse identify doctors and other health professionals as …

Purpose Patient-reported outcome measures (PROMs) are increasingly used in clinical settings
to inform individual patient care. In-depth understanding of end-users’ experiences may …

Background The effectiveness of intermittent montelukast for wheeze in young children is
unclear. We aimed to assess whether intermittent montelukast is better than placebo for …

… The only exception was the STAR-C, which was independently self-rated by clinicians. A
total of 6 researchers were involved in the assessment of outcomes. Interrater reliability for the …

The prostate cancer detection rate from screening by digital rectal examination and tactilely
guided prostate biopsy is approximately 1.7%. Among 1,807 men a detection rate of 14.6% …

Almost half of all enzymes must associate with a particular metal to function. An ambition is
to understand why each metal–protein partnership arose and how it is maintained. Metal …