Cardiac side effects of the cytostatic agent 5-fluorouracil (5-FU) have an incidence of 1.2-
7.6%. Potentially, arrhythmias, myocardial infarction and sudden cardiac death could occur …

The clinical coincidence of osteoporosis and vascular disease has long indicated that common
mediators may adversely affect bone metabolism and vascular integrity alike. Receptor …

Osteoprotegerin (OPG) regulates osteoclast and immune functions and appears to
represent a protective factor for the vascular system. However, the role of OPG in human …

Background— Cytochrome P450 (CYP) 2J2 is expressed in the vascular endothelium and
metabolizes arachidonic acid to biologically active epoxyeicosatrienoic acids (EETs). The …

Background/objective: Chest pain is a common complaint and reason for consultation. We
aimed to study the epidemiology of chest pain with respect to underlying aetiologies and to …

Context: Free fatty acids (FFAs) are associated with several cardiovascular risk factors and
exert harmful effects on the myocardium. Objective: The aim of our study was to elucidate the …

Background: Chest pain can be caused by various conditions, with life-threatening cardiac
disease being of greatest concern. Prediction scores to rule out coronary artery disease have …

The assassination of Julius Caesar in 44 BCE triggered a power struggle that ultimately
ended the Roman Republic and, eventually, the Ptolemaic Kingdom, leading to the rise of the …

Osteoprotegerin (OPG) antagonizes receptor activator of nuclear factor-κB ligand (RANKL),
the principal regulator of osteoclasts. Of note, OPG-deficient mice display osteoporosis and …

Deficiency of the cholesteryl ester transfer protein (CETP) in humans is characterized by
markedly elevated plasma concentrations of HDL cholesterol and apoA-I. To assess the …