Objective Every year, thousands of patients with peripheral vascular disease undergo major
lower limb amputation. Despite this, evidence for optimal management is weak. Core …

BACKGROUND Interventions promoting evidence based antibiotic prescribing and use
frequently build on the concept of antibiotic resistance but patients and clinicians may not share …

Objective To determine if guided internet based cognitive behavioural therapy with a trauma
focus (CBT-TF) is non-inferior to individual face-to-face CBT-TF for mild to moderate post-…

BACKGROUND Evidence shows a high rate of unnecessary antibiotic prescriptions in primary
care in Europe and the United States. Given the costs of widespread use and associated …

Objectives There is a wide variation between European countries in antibiotic prescribing for
patients in primary care with lower respiratory tract infection (LRTI) that is not explained by …

Objectives There is variation in antibiotic prescribing for lower respiratory tract infections (LRTI)
in primary care that does not benefit patients. This study aims to investigate clinicians' …

Background Autism spectrum disorder (ASD) is a common lifelong condition affecting 1 in
100 people. ASD affects how a person relates to others and the world around them. Difficulty …

Background. Point of care tests (POCTs) are being promoted to better target antibiotic prescribing
with the aim of improving outcomes and containing antibiotic resistance. Objective. We …

Objectives To explore and compare primary care clinicians' perceptions of antibiotic resistance
in relation to the management of community-acquired lower respiratory tract infection (…

Background Carers report unmet need for occupational therapy services addressing sensory
difficulties in autism, yet insufficient evidence exists to recommend a therapeutic approach. …