Background In primary care settings, the diagnosis of rhinosinusitis is generally based on
clinical signs and symptoms. Technical investigations are not routinely performed, nor …

Background Acute rhinosinusitis is an acute infection of the nasal passages and paranasal
sinuses that lasts less than four weeks. Diagnosis of acute rhinosinusitis is generally based …

Background Point-of-care blood C-reactive protein (CRP) testing has diagnostic value in
helping clinicians rule out the possibility of serious infection. We investigated whether it should …

Background Antibiotics are overprescribed for non-severe acute infections in children in
primary care. Aim To explore two different interventions that may reduce inappropriate antibiotic …

Objective Acute infection is the most common presentation of children in primary care with
only few having a serious infection (eg, sepsis, meningitis, pneumonia). To avoid …

Objective: Antibiotics are prescribed too often in acutely ill children in primary care. We
examined whether a Point-of-Care (POC) C-reactive Protein (CRP) test influences the family …

Objective Acute infection is the most common presentation of children to hospital. A minority
of these infections are serious, but early recognition and adequate management are …

Background Despite huge public campaigns, there is still overconsumption of antibiotics in
children with self-limiting diseases. Possible explanations may be the physicians’ and parents…

… In the ERNIE 2 trial, we will provide formal safety netting to a random sample of all children
with a negative result on the decision tree, as described by Lemiengre et al. [22]. This …

After publication of the original article [1], it was brought to the authors attention that the
discussion section needed an extension regarding issues raised during the peer review process. …