… Declaration of competing interests: Nicky Welton has … (application areas unknown to Dr
Welton), Pfizer (teaching only), … In all cases, Dr Welton was blind to the included treatments. …

Objective To determine the effect of glucosamine, chondroitin, or the two in combination on
joint pain and on radiological progression of disease in osteoarthritis of the hip or knee. …

This paper sets out a generalised linear model (GLM) framework for the synthesis of data
from randomised controlled trials (RCTs). We describe a common model taking the form of a …

… set n ^ l o w e r i = n r i s k i . This produces an estimated number at risk at the start of the
following interval n r î s k i + 1 = n ^ … If n r î s k i + 1 ≠ n r i s k i + 1 then we re-adjust the estimated …

… Psaty B, Lumley T, Furberg C, Schellenbaum G, Pahor M, Alderman M, Weiss N. Health …
Welton NJ, Ades AE. A model of toxoplasmosis incidence in the UK: evidence synthesis and …

We set out a generalized linear model framework for the synthesis of data from randomized
controlled trials. A common model is described, taking the form of a linear regression for both …

Published evidence suggests that aspects of trial design lead to biased intervention effect
estimates, but findings from different studies are inconsistent. This study combined data from 7 …

Objective To generate global and regional estimates for the prevalence and incidence of
herpes simplex virus (HSV) type 1 and type 2 infection for 2016. Methods To obtain data, we …

… For example, an indirect estimate d ^ B D I n d can be formed as d ^ B D I n d = d ^ A C D i r
− d ^ A B D i r + d ^ C D D i r , by successive application of the consistency equations. Clearly, …

… For a dichotomous variable (the occurrence or nonoccurrence of an event), for every clinical
trial i and for each included treatment x, we have the sample size n i,x and the number of …