Primary prevention of major cardiovascular and cerebrovascular events with statins in diabetic patients: a meta-analysis

FM De Vries, P Denig, KB Pouwels, MJ Postma, E Hak - Drugs, 2012 - Springer
Background Patients with diabetes mellitus are at increased risk of developing cardiovascular
disease. Controlling lipid levels has a preventive effect on the occurrence of major …

Rates, determinants and success of implementing deprescribing in people with type 2 diabetes: a scoping review

MP Oktora, KP Kerr, E Hak, P Denig - Diabetic Medicine, 2021 - Wiley Online Library
Background Individualizing goals for people with type 2 diabetes may result in deintensification
of medication, but a comprehensive picture of deprescribing practices is lacking. Aims To …

Precision medicine approaches for diabetic kidney disease: opportunities and challenges

SC Tye, P Denig, HJL Heerspink - Nephrology Dialysis …, 2021 - academic.oup.com
The prevalence of end-stage kidney disease (ESKD) continuously increases worldwide. The
increasing prevalence parallels the growth in the number of people with diabetes, which is …

[HTML][HTML] Medication beliefs, treatment complexity, and non-adherence to different drug classes in patients with type 2 diabetes

…, FM Haaijer-Ruskamp, J Voorham, P Denig - Journal of …, 2014 - Elsevier
… For blood pressure-lowering drugs, patients reporting intentional non-adherence had higher
concern beliefs than adherers (8 point difference, P = 0.01). Treatment complexity scores …

Sex differences in adverse drug reactions reported to the National Pharmacovigilance Centre in the Netherlands: An explorative observational study

ST de Vries, P Denig, C Ekhart… - British journal of …, 2019 - Wiley Online Library
Aims: We aimed to assess and characterize sex differences in adverse drug reactions (ADRs)
reported to the national pharmacovigilance centre in the Netherlands while considering …

How physicians choose drugs

P Denig, FM Haaijer-Ruskamp, DH Zijsling - Social science & medicine, 1988 - Elsevier
A drug choice model which includes the physician's attitudes, norms and personal experiences
with drugs, was tested. One hundred and sixty-nine physicians were asked the estimate …

Comparison of various measures for assessing medication refill adherence using prescription data

…, OH Klungel, RP Stolk, P Denig - … and drug safety, 2009 - Wiley Online Library
Background Several measures using prescription data have been developed for estimating
medication refill adherence. Few studies have made direct comparisons, and little is known …

[HTML][HTML] Trends in polypharmacy and dispensed drugs among adults in the Netherlands as compared to the United States

MP Oktora, P Denig, JHJ Bos, CCM Schuiling-Veninga… - PloS one, 2019 - journals.plos.org
Background and purpose Polypharmacy is becoming increasingly common owing to the
ageing population, which can pose problems for patients and society. We investigated the …

Trends in polypharmacy and potentially inappropriate medication (PIM) in older and middle‐aged people treated for diabetes

…, K Taxis, E Hak, P Denig - British Journal of …, 2021 - Wiley Online Library
Aims Polypharmacy is common in people with diabetes and is associated with the use of
potentially inappropriate medication (PIM). This study aimed to assess trends in the prevalence …

[HTML][HTML] A longitudinal study examining adherence to guidelines in diabetes care according to different definitions of adequacy and timeliness

…, FM Haaijer-Ruskamp, D de Zeeuw, P Denig - PloS one, 2011 - journals.plos.org
… Mean changes in HbA1c significantly improved and leveled off after 20 days since treatment
intensification (p = 0.04). The quality score regarding adequate management reduced …