Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years

…, FAM van Balen, AW Hoes, TJM Verheij, RA de Melker - Bmj, 2000 - bmj.com
… Adverse effects—De novo diarrhoea was reported on day four in 17% (20/117) of the
amoxicillin group and in 10% (12/123) of the placebo group (… De Melker RADe Melker RA

Penicillin for acute sore throat: randomised double blind trial of seven days versus three days treatment or placebo in adults

…, GJHM Ruijs, JW Gubbels, AW Hoes, RA de Melker - Bmj, 2000 - bmj.com
Objective: To assess whether treatment with penicillin for three days and the traditional
treatment for seven days were equally as effective at accelerating resolution of symptoms in …

Nontraumatic foot complaints in older people. A population-based survey of risk factors, mobility, and well-being

…, MM Kuyvenhoven, RA de Melker - Journal of the …, 2000 - Am Podiatric Med Assoc
In a population-based cross-sectional survey conducted in the Netherlands of 7,200 people
aged 65 years and older (with a response rate of 79%), 20% of the respondents were found …

Penicillin for acute sore throat in children: randomised, double blind trial

S Zwart, MM Rovers, RA de Melker, AW Hoes - Bmj, 2003 - bmj.com
ObjectiveTo assess the effectiveness of penicillin for three days and treatment for seven
days compared with placebo in resolving symptoms in children with sore throat. …

The sickness impact profile; results of an evaluation study of the Dutch version

…, A Luttik, FW Touw-Otten, RA De Melker - Nederlands tijdschrift …, 1990 - europepmc.org
The US clinimetric instrument, the sickness impact profile (SIP), was validated for The
Netherlands. The SIP is a standardized list of 136 statements aimed at measuring changes of …

Do patients with sore throat benefit from penicillin? A randomized double-blind placebo-controlled clinical trial with penicillin V in general practice.

CF Dagnelie, Y Van der Graaf, RA De Melker - British Journal of General …, 1996 - bjgp.org
BACKGROUND: The effect of antibiotic therapy in sore throat is questionable and this
dilemma has been complicated by the emergence of multiple resistant strains of micro-organisms. …

Is immunising all patients with chronic lung disease in the community against influenza cost effective? Evidence from a general practice based clinical prospective …

…, E Buskens, W Stalman, RA De Melker - … of Epidemiology & …, 1998 - jech.bmj.com
STUDY OBJECTIVE: There is little information on the potential benefit of immunising all patients
with chronic lung disease in the community against influenza. The clinical effectiveness …

Why do healthy elderly people fail to comply with influenza vaccination?

…, MM Kuyvenhoven, RADE MELKER - Age and …, 1997 - academic.oup.com
Objective: to assess motivating factors of healthy elderly people to comply with influenza
vaccination. Design:survey of healthy elderly people invited by mail by their general practitioner …

The end of antibiotic treatment in adults with acute sinusitis-like complaints in general practice? A placebo-controlled double-blind randomized doxycycline trial.

…, GA Van Essen, Y Van der Graaf, RA De Melker - British journal of general …, 1997 - bjgp.org
BACKGROUND: Acute sinusitis-like complaints are very common and are usually treated with
antibiotics in spite of the lack of evidence for the effectiveness of antibiotic therapy and the …

Antibiotic treatment of acute otitis media in children under two years of age: evidence based?

…, FA Van Balen, AW Hoes, RA de Melker - British journal of general …, 1998 - bjgp.org
BACKGROUND: Appropriate use of antibiotics is one of the major issues in medicine today.
In most countries, acute otitis media in children is treated with antibiotics; however, the …