The intestinal microbiota plays a fundamental role in maintaining immune homeostasis. In
controlled clinical trials probiotic bacteria have demonstrated a benefit in treating …

This Review provides an updated approach to the diagnosis of idiopathic pulmonary fibrosis
(IPF), based on a systematic search of the medical literature and the expert opinion of …

Inflammatory bowel diseases are characterised by inflammation that compromises the
integrity of the epithelial barrier. The intestinal epithelium is not only a static barrier but has …

On 24 th November 2021, the sequence of a new SARS-CoV-2 viral isolate Omicron-B.1.1.529
was announced, containing far more mutations in Spike (S) than previously reported …

Background: This document provides clinical recommendations for the diagnosis of
idiopathic pulmonary fibrosis (IPF). It represents a collaborative effort between the American …

… In patients with suspected VAP, we recommend including coverage for S. aureus,
Pseudomonas aeruginosa, and other gram-negative bacilli in all empiric regimens (strong …

… The systematic review that informed the committee’s recommendation is published
independently (76); we summarize the salient findings. Diagnostic test characteristics were rated as …

Objective To develop and validate a pragmatic risk score to predict mortality in patients admitted
to hospital with coronavirus disease 2019 (covid-19). Design Prospective observational …

Defective dendritic cell (DC) function caused by abnormal differentiation of these cells is an
important mechanism of tumor escape from immune system control. Previously, we have …

X-linked recessive dyskeratosis congenita (DKC) is a rare bone-marrow failure disorder linked
to Xq28. Hybridization screening with 28 candidate cDNAs resulted in the detection of a 3…