Objective: To investigate the validity of spirometric tests performed in general practice.
Method: A repeated within subject comparison of spirometric tests with a “gold standard” (…

Objective: To critically appraise and summarize the quality of the measurement properties of
the Dizziness Handicap Inventory's (DHI) in adult patients with complaints of dizziness.

Background COPD often coexists with chronic conditions that may influence disease
prognosis. We investigated associations between chronic (co)morbidities and exacerbations in …

To reduce the burden of chronic diseases on society and individuals, European countries
implemented chronic Disease Management Programs (DMPs) that focus on the management …

Background Scientific evidence on how to manage multimorbidity is limited, but GPs have
extensive practical experience with multimorbidity management. Aim To explore GPs’ …

Protein-energy malnutrition is thought to be widespread in hospitalized patients. However,
the specificity of indexes used to assess malnutrition is uncertain. We therefore assessed the …

OBJECTIVE: To examine the difference between patients with normal and patients with
abnormal fatigue on aspects of health status, and investigate the natural course of fatigue in …

Background Primary aldosteronism (PA) is the most frequent cause of secondary hypertension.
Reported prevalences of PA vary considerably because of a large heterogeneity in study …

Clinical guidelines indicate that a chronic obstructive pulmonary disease (COPD) diagnosis
is made from a single spirometry test. However, long-term stability of diagnosis based on …

In this randomized controlled economic evaluation we compared guided asthma self-management
with usual asthma care according to guidelines for Dutch family physicians. Nineteen …