User profiles for T. Afzali
tamana afzaliThe Research Unit for General Practice in Aalborg Verified email at dcm.aau.dk Cited by 66 |
[HTML][HTML] Cost-effectiveness of treatments for non-osteoarthritic knee pain conditions: A systematic review
Introduction Knee pain is common in adolescents and adults and is associated with an
increased risk of developing knee osteoarthritis. The aim of this systematic review was to gather …
increased risk of developing knee osteoarthritis. The aim of this systematic review was to gather …
Effect of differentiating exercise guidance based on a patient's level of low back pain in primary care: a mixed-methods systematic review protocol
Introduction Low back pain (LBP) is one of the health conditions that lead to the most disability
worldwide. Guidelines aimed at management of LBP recommend non-invasive and non-…
worldwide. Guidelines aimed at management of LBP recommend non-invasive and non-…
The role of T helper 17 (Th17) and regulatory T cells (Treg) in human organ transplantation and autoimmune disease
B Afzali, G Lombardi, RI Lechler… - Clinical & Experimental …, 2007 - academic.oup.com
… , T-bet for Th1, GATA-3 for Th2, forkhead box P3 (FoxP3) for T regs and RORγt for Th17 cells.
Recently, it has been demonstrated that the skewing of murine Thp towards Th17 and T … T …
Recently, it has been demonstrated that the skewing of murine Thp towards Th17 and T … T …
T helper 1 immunity requires complement-driven NLRP3 inflammasome activity in CD4+ T cells
… for complement C3 also in human T cell immunity: The … T cell lineage commitment, and
they control initiation and resolution of T helper 1 (T H 1) responses in an autocrine fashion via T …
they control initiation and resolution of T helper 1 (T H 1) responses in an autocrine fashion via T …
[PDF][PDF] Intracellular complement activation sustains T cell homeostasis and mediates effector differentiation
… T cell-expressed protease cathepsin L (CTSL) processed C3 into biologically active C3a and
C3b. Resting T … While "tonic" intracellular C3a generation was required for homeostatic T …
C3b. Resting T … While "tonic" intracellular C3a generation was required for homeostatic T …
IL‐17‐producing CD4+ T cells, pro‐inflammatory cytokines and apoptosis are increased in low risk myelodysplastic syndrome
SY Kordasti, B Afzali, Z Lim, W Ingram… - British journal of …, 2009 - Wiley Online Library
… CD8 + T cells in all subtypes of MDS, we speculated that the mechanism of inflammatory
response in low risk MDS might be correlated with an increased number of pro-inflammatory T-…
response in low risk MDS might be correlated with an increased number of pro-inflammatory T-…
CD4+CD25high Foxp3+ regulatory T cells in myelodysplastic syndrome (MDS)
…, J Hayden, D Darling, L Barber, B Afzali… - Blood, The Journal …, 2007 - ashpublications.org
Foxp3 + regulatory T cells (Tregs) play a central role in maintaining immune tolerance. A
reduction in the function of Tregs is a key feature of autoimmune diseases, whereas their …
reduction in the function of Tregs is a key feature of autoimmune diseases, whereas their …
Translational mini-review series on Th17 cells: induction of interleukin-17 production by regulatory T cells
… towards T helper type 1 (Th1), Th2, Th17 and regulatory T cell (T reg … T-bet for Th1, GATA-3
for Th2, forkhead box P3 (FoxP3) for T … In this paper, we review T reg to Th17 conversion and …
for Th2, forkhead box P3 (FoxP3) for T … In this paper, we review T reg to Th17 conversion and …
CD 161 expression characterizes a subpopulation of human regulatory T cells that produces IL‐17 in a STAT 3‐dependent manner
B Afzali, PJ Mitchell, FC Edozie… - European journal of …, 2013 - Wiley Online Library
… T reg cells from patients with STAT 3 mutations unable to make IL ‐17. Finally, we show that
CD 161 + population III T … T reg‐cell population at these sites. As IL ‐17 production from this …
CD 161 + population III T … T reg‐cell population at these sites. As IL ‐17 production from this …
Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease
…, JD Sanderson, JK Howard, S Yagel, B Afzali… - Gut, 2016 - gut.bmj.com
Background and aim Thymus-derived regulatory T cells (T regs ) mediate dominant peripheral
tolerance and treat experimental colitis. T regs can be expanded from patient blood and …
tolerance and treat experimental colitis. T regs can be expanded from patient blood and …