PURPOSE Nifedipine is commonly prescribed for the treatment of chilblains (pernio, perniosis)
on the basis of observational studies and a single small, older clinical trial. We aimed to …

Background GPs prescribe topical corticosteroids to patients with chronic chilblains despite
poor evidence for their effectiveness. The authors of the current study therefore decided to …

Chronic chilblains are cold induced, painful or itching, red-blue lesions on the fingers, feet,
ears, or thighs (fig). 1 The condition occurs throughout the world, more commonly in women …

Background: Chronic chilblains is a common disease causing major restrictions in daily life,
nevertheless little is known about effective treatment. In a literature search, we found thin …

… Souwer … i.souwer@wxs.nl … Souwer IH, Lagro-Janssen ALM. Vitamin D3 is not
effective in the treatment of chronic chilblains Submitted. …

Background. Our clinical observations and two earlier studies indicate familial clustering to
be involved in chronic chilblains. Demonstrating phenotypic familial aggregation is a next …

For centuries, doctors have recognised patients with complaints of a cold-induced condition
known as perniones or chilblains but the backgrounds of the condition are largely unknown. …

Chronic chilblains is generally considered by doctors to be a slightly inconvenient and
harmless condition. We observed that a large number of our patients showed unexpectedly …

Background: Chronic chilblains is a common disease causing major restrictions in daily life,
nevertheless little is known about effective treatment. In a literature search, we found thin …

… In this study, orange, tomato, apple juices, and sour cherry nectar were exposed to an
atmospheric pressure plasma jet. Plasma treatments were carried out using air as a precursor …