RESEARCH Page 1 Factors associated with the presence of diabetic ketoacidosis at
diagnosis of diabetes in children and young adults: a systematic review Juliet A Usher-Smith …

Background A significant proportion of the worldwide population is at risk of social isolation
and loneliness as a result of the COVID-19 pandemic. We aimed to identify effective …

Aims/hypothesis Type 1 diabetes is the most frequent endocrine disease in children, with
65,000 children diagnosed worldwide every year. Up to 80% of these children present with …

The spectrum effect describes the variation between settings in performance of tests used to
predict, screen for, and diagnose disease. In particular, the predictive use of a test may be …

Background Systematic reviews are vital to the pursuit of evidence-based medicine within
healthcare. Screening titles and abstracts (T&Ab) for inclusion in a systematic review is an …

Structured Abstract Aims To estimate development of type 2 diabetes (T2DM) in women with
previous gestational diabetes (GDM) and investigate characteristics associated with higher …

Update to this article In October 2022, three years after the initial publication of this guideline,
the first trial of the effect of colonoscopy screening was published. The implications of this …

… JA Usher-Smith is funded by a National Institute of Health Research (NIHR) Clinical
Lectureship and FM Walter by an NIHR Clinician Scientist award. JD Emery is funded by an …

… One reviewer (JA Usher-Smith) performed the search and screened the titles and
abstracts to exclude articles that were clearly not relevant. A second reviewer (FM Walter) …

Aims After gestational diabetes, many women exhibit behaviours that increase their risk of
developing Type 2 diabetes. We aimed to systematically synthesize the literature that focuses …