The natural history of cervical HPV infection: unresolved issues

CBJ Woodman, SI Collins, LS Young - Nature Reviews Cancer, 2007 - nature.com
The identification of high-risk human papillomavirus (HPV) types as a necessary cause of
cervical cancer offers the prospect of effective primary prevention and the possibility of …

[HTML][HTML] A phase I/II clinical trial in localized prostate cancer of an adenovirus expressing nitroreductase with CB1984

…, D Ashdown, S Bonney, RG Pineda, SI Collins… - Molecular therapy, 2009 - cell.com
We report a phase I/II clinical trial in prostate cancer (PCa) using direct intraprostatic injection
of a replication defective adenovirus vector (CTL102) encoding bacterial nitroreductase (…

Oncogenic human papillomavirus imposes an instructive pattern of DNA methylation changes which parallel the natural history of cervical HPV infection in young …

SM Leonard, W Wei, SI Collins, M Pereira… - …, 2012 - academic.oup.com
The contribution of early virus-induced epigenetic changes to human papillomavirus (HPV)-associated
carcinogenesis is poorly understood. Using genome-wide methylation array …

Disruption of the E2 Gene Is a Common and Early Event in the Natural History of Cervical Human Papillomavirus Infection: A Longitudinal Cohort Study

SI Collins, C Constandinou-Williams, K Wen, LS Young… - Cancer research, 2009 - AACR
Integration of high-risk human papillomavirus (HPV) types into the host-cell genome disrupts
the HPV regulatory E2 protein, resulting in a loss of negative feedback control of viral …

Mechanisms of recurrence of Ta/T1 bladder cancer

RT Bryan, SI Collins, MC Daykin… - The Annals of The …, 2010 - publishing.rcseng.ac.uk
INTRODUCTION Bladder cancer recurrence occurs via four mechanisms - incomplete resection,
tumour cell re-implantation, growth of microscopic tumours, and new tumour formation. …

Narrow-band imaging flexible cystoscopy: a new user's experience

RT Bryan, ZH Shah, SI Collins… - Journal of …, 2010 - liebertpub.com
Background and Purpose: We and others have demonstrated previously an improved detection
rate for bladder cancer recurrences with narrow-band imaging (NBI) flexible cystoscopy …

Implementation of RCGP guidelines for acute low back pain: a cluster randomised controlled trial.

P Dey, CWR Simpson, SI Collins, G Hodgson… - British Journal of …, 2004 - bjgp.org
… P Dey, MD, MFPHM, lecturer in public health and deputy director; SI Collins, BSc, statistician,
Centre for Cancer Epidemiology, University of Manchester. CWR Simpson, MFPHM, …

Is human papillomavirus viral load a clinically useful predictive marker? A longitudinal study

C Constandinou-Williams, SI Collins, S Roberts… - … , biomarkers & prevention, 2010 - AACR
… Constandinou-Williams and SI Collins contributed equally to this work. C. Constandinou-…
SI Collins designed the study, analyzed and interpreted the data, drafted the article, revised …

A study of split-dose cisplatin-based neo-adjuvant chemotherapy in muscle-invasive bladder cancer

…, DH Palmer, B Lloyd, SI Collins… - Oncology …, 2012 - spandidos-publications.com
The aim of this study was to investigate the outcome of patients with muscle-invasive
bladder cancer (MIBC) receiving neo-adjuvant chemotherapy (neo-CT) using a cisplatin-based …

Proximity of first intercourse to menarche and the risk of human papillomavirus infection: a longitudinal study

SI Collins, S Mazloomzadeh, H Winter… - … journal of cancer, 2005 - Wiley Online Library
Cross‐sectional studies have suggested that compared with women who delay the start of
their sexual career, those who first have intercourse soon after menarche are more …