The blood–brain barrier (BBB) excludes the vast majority of cancer therapeutics from
normal brain. However, the importance of the BBB in limiting drug delivery and efficacy is …

Objective: Deficits in social functioning are a core feature of schizophrenia. Method: A
literature search of English language articles published between January 1990 and December …

… It also acts as an antigen for B and T-lymphocytes and is a ligand for Toll-like receptor,
hence is involved in immune system regulation [162]. HSP60 plays vital roles in transformation, …

First published in 1961, this book is a very influential book on organization theory and
industrial sociology. The central theme of the book is the relationship between an organization …

Background Obesity in childhood is associated with increased cardiovascular risk. It is uncertain
whether this risk is attenuated in persons who are overweight or obese as children but …

Background No therapies for targeting KRAS mutations in cancer have been approved. The
KRAS p.G12C mutation occurs in 13% of non–small-cell lung cancers (NSCLCs) and in 1 to …

The late Arthur Rook established the Textbook of Dermatologyas the most comprehensive
work of reference available to thedermatologist and it enjoys instant name recognition. …

Background KRAS p.G12C mutation occurs in approximately 1 to 2% of pancreatic cancers.
The safety and efficacy of sotorasib, a KRAS G12C inhibitor, in previously treated patients …

Science communication is a growing area of practice and research. During the past two
decades, the number of activities, courses, and practitioners has steadily increased. But what …

Background The value of the individual placement and support (IPS) programme in helping
people with severe mental illness gain open employment is unknown in Europe. Our aim …