Faecal calprotectin in older adults
There is uncertainty surrounding the use of faecal calprotectin (FC) as a diagnostic test in older adults. This study investigates the performance of FC in patients ≥50 years and, where available, FIT was also analysed. Data suggest that FC is a sensitive test for IBD and organic gastrointestinal (GI) pathology in older adults. However, in this group, FC should not be used where colorectal cancer is suspected. FC may have a role as a 'rule out' test in older adults with lower GI symptoms and a negative FIT, provided that there is no suspicion of colorectal cancer.