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British Journal of General Practice

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Research Article

Follow-up, treatment, and reinfection rates among asymptomatic chlamydia trachomatis cases in general practice.

Irene G M van Valkengoed, Servaas A Morré, Adriaan J C van den Brule, Chris J L M Meijer, Lex M Bouter, Jacques Th M van Eijk and A Joan P Boeke
British Journal of General Practice 2002; 52 (481): 623-627.
Irene G M van Valkengoed
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Servaas A Morré
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Adriaan J C van den Brule
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Chris J L M Meijer
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Lex M Bouter
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Jacques Th M van Eijk
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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A Joan P Boeke
Department of Pathology, University Hospital, Vrije Universiteit, Amsterdam, The Netherland.
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Abstract

BACKGROUND: Adequate treatment and follow-up of patients is essential to the success of a screening programme for Chlamydia trachomatis. There has been a lack of data on follow-up, confirmation of infections, and reinfection rates among asymptomatic patients in general practice. AIM: 7b study the rates of diagnostic confirmation of C trachomatis infection, successful treatment, and reinfection one year after cases were detected in a screening programme for asymptomatic infections. DESIGN OF STUDY: Prospective cohort study SETTING: Fifteen general practices in Amsterdam, The Netherlands. METHOD: One hundred and twenty-four patients with asymptomatic C trachomatis infections were requested to provide a cervical or urethral swab and a urine specimen, for the purpose of diagnostic confirmation before being treated. One year after the first screening, all of the patients were invited for a second screening. All samples were tested using the ligase chain reaction (Abbott Laboratories, Chicago, USA). RESULTS: Out of 124 patients, 110 (89%) attended the scheduled appointment for diagnostic confirmation and treatment; 92 (84%) of them were confirmed to be positive and received treatment. At the second screening a year later, none of the 56 patients who had received treatment and who had been screened a second time were reinfected. CONCLUSION: No asymptomatic patients werefound to have reinfections with C trachomatis one year after diagnostic confirmation and treatment. This underlines the effectiveness of the screening and treatment strategy

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British Journal of General Practice: 52 (481)
British Journal of General Practice
Vol. 52, Issue 481
August 2002
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Follow-up, treatment, and reinfection rates among asymptomatic chlamydia trachomatis cases in general practice.
Irene G M van Valkengoed, Servaas A Morré, Adriaan J C van den Brule, Chris J L M Meijer, Lex M Bouter, Jacques Th M van Eijk, A Joan P Boeke
British Journal of General Practice 2002; 52 (481): 623-627.

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Follow-up, treatment, and reinfection rates among asymptomatic chlamydia trachomatis cases in general practice.
Irene G M van Valkengoed, Servaas A Morré, Adriaan J C van den Brule, Chris J L M Meijer, Lex M Bouter, Jacques Th M van Eijk, A Joan P Boeke
British Journal of General Practice 2002; 52 (481): 623-627.
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Print ISSN: 0960-1643
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