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British Journal of General Practice

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Original Papers

C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis

Lars Bjerrum, Bente Gahrn-Hansen and Anders P Munck
British Journal of General Practice 2004; 54 (506): 659-662.
Lars Bjerrum
Roles: Senior Researcher
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Bente Gahrn-Hansen
Roles: Consultant and Associate Professor
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Anders P Munck
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    Figure 1

    Relation between level of C-reactive protein, number of patients treated with sinusitis and antibiotic treatment.

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    Table 1

    Comparison between practices that use the C-reactive protein rapid test and practices that do not.

    Practices using CRP rapid tests (n = 281)Practices not using CRP rapid tests (n = 86)
    Antibiotic prescribing rate for upper RTIs (% [95% CI])
     Acute sinusitis59 (56 to 62)78 (73 to 82)
     Acute tonsillitis42 (40 to 44)46 (42 to 50)
     Acute otitis48 (45 to 50)48 (43 to 53)
    RTI patient characteristics
     Median (IQR) age of patients with RTIs in years26 (4–47)27 (4–48)
     Median (IQR) age of patients with sinusitis in years40 (31–53)41 (31–54)
     Percentage (95% CI) of female patients with RTIs56 (55 to 57)59 (57 to 60)
     Percentage (95% CI) of female patients with sinusitis68 (65 to 71)72 (67 to 76)
     Median (IQR) of patients with RTIs per GP47 (34–58)47 (35–70)
    Practice characteristics
     Percentage (95% CI) of GPs in group practices64 (58 to 70)57 (48 to 68)
     Median (IQR) of patients listed per practice2150 (1600–3900)1875 (1610–3050)
     Median (IQR) age of GPs (years)49 (45–54)52 (46–56)
     Percentage (95% CI) of female GPs36 (25 to 47)38 (32 to 45)
     Percentage (95% CI) of GPs with high workloada50 (44 to 56)55 (44 to 66)
    • ↵aSelf-assessed. CRP = C-reactive protein; IQR = interquartile range; RTI = respiratory tract infection.

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    Table 2

    Results of logistic regression relating access to CRP and practice characteristics to prescription of antibiotics.

    CharacteristicOdds ratio95% CI
    Access to CRP testing (yes/no)0.430.33 to 0.58
    Type of practice (single-handed/group)1·411.12 to 1.77
    • CRP = C-reactive protein.

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British Journal of General Practice: 54 (506)
British Journal of General Practice
Vol. 54, Issue 506
September 2004
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C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis
Lars Bjerrum, Bente Gahrn-Hansen, Anders P Munck
British Journal of General Practice 2004; 54 (506): 659-662.

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C-reactive protein measurement in general practice may lead to lower antibiotic prescribing for sinusitis
Lars Bjerrum, Bente Gahrn-Hansen, Anders P Munck
British Journal of General Practice 2004; 54 (506): 659-662.
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Keywords

  • antibiotics
  • C-reactive protein
  • general practice
  • sinusitis

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