New Eng J Med Vol 353
1095 Scanning the specialist cardiology journals and the general medical ones, no week goes by without at least one new paper on immediate percutaneous intervention (PCI) for acute coronary syndromes. Here's one from the Netherlands; the Eur Heart J (26: 1956) has one from Leipzig, and Heart (91: 1284,1330) has one from both Arezzo and Middlesbrough. Each has a slightly different twist, and two carry the message that immediate PCI has no significant benefit over delayed PCI after thrombolyis in real-life settings. However, Leipzig, Arezzo and the three RITA trials (Lancet 366: 914) suggest otherwise. Meanwhile, JAMA (294: 1224) demonstrates that all these PCI patients should have clopidogrel too.
1209 This trial compared the effect of new antipsychotic drugs with perphenazine. Its main finding was that you cannot get 75% of schizophrenic patients to take the same drug for 18 months. Olanzapine takers keep on the longest, …