New Eng J Med Vol 353–354
2433 Clostridium is getting more difficile, probably due to increasing use of quinolone antibiotics, selecting aggressive subtypes which are quinolone-resistant. And the bug is getting commoner due to wide use of proton pump inhibitors (JAMA 295: 2989).
2462 Ulcerative colitis responds well to the anti-TNF monoclonal antibody infliximab, without any serious side-effects in two trials.
2539 At every contraceptive update you've been to, you'll have been told not to prescribe the combined pill to women with systemic lupus erythematosus: this prospective study, and another on page 2550, shows that it is safe to do so.
2559 Influenza vaccine annually for all children under 5? In the winter of 2003–2004, over 150 children died of influenza-related causes in the US, and only a third had identifiable risk factors.
2643 UKPDS may leave doubts about the value of tight control in type 2 diabetes, but in type …