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Research

Prevalence of treatment-resistant depression in primary care: cross-sectional data

Laura Thomas, David Kessler, John Campbell, Jill Morrison, Tim J Peters, Chris Williams, Glyn Lewis and Nicola Wiles
British Journal of General Practice 2013; 63 (617): e852-e858. DOI: https://doi.org/10.3399/bjgp13X675430
Laura Thomas
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David Kessler
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John Campbell
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Jill Morrison
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Tim J Peters
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Chris Williams
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Glyn Lewis
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Nicola Wiles
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  • Treatment-resistant depression
    Chris Manning
    Published on: 16 December 2013
  • Published on: (16 December 2013)
    Page navigation anchor for Treatment-resistant depression
    Treatment-resistant depression
    • Chris Manning, Retired GP, Director Upstream Healthcare Ltd and Chair Faculty of Mental Health, College of Medicine

    I used to wonder as a GP what chance an active molecule on its own might have in addressing the depressions I saw in various patients. I now understand far better the importance of the placebo effect (another coverall term for a whole raft of inter and intra-human complex processes) and of the contexts in which a life is lived.

    As the study by Thomas et al demonstrates, over 50% of patient depressions fail to re...

    Show More

    I used to wonder as a GP what chance an active molecule on its own might have in addressing the depressions I saw in various patients. I now understand far better the importance of the placebo effect (another coverall term for a whole raft of inter and intra-human complex processes) and of the contexts in which a life is lived.

    As the study by Thomas et al demonstrates, over 50% of patient depressions fail to respond after 6 weeks of adequate doses of antidepressants 'emphasising the need for regular review'. One would hope that such review would include a thorough assessment of associated morbidities and biopsychosocial, and dare I say it spiritual, factors if any molecule is to stand a chance against, for example, a background of abuse at home, bullying at work or debt. To say nothing of the other available approaches for depressions, such as mindfulness, systemic therapies and Men Sheds.

    Doctors should be in the business of working with others to address such issues and needs, not merely assessing them and labelling people as 'treatment-resistant'. We can hit the television for all it is worth, but it is always worth ensuring the presence of connection to current and a good signal?

    Conflict of Interest:

    None declared

    Show Less
    Competing Interests: None declared.
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British Journal of General Practice: 63 (617)
British Journal of General Practice
Vol. 63, Issue 617
December 2013
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Prevalence of treatment-resistant depression in primary care: cross-sectional data
Laura Thomas, David Kessler, John Campbell, Jill Morrison, Tim J Peters, Chris Williams, Glyn Lewis, Nicola Wiles
British Journal of General Practice 2013; 63 (617): e852-e858. DOI: 10.3399/bjgp13X675430

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Prevalence of treatment-resistant depression in primary care: cross-sectional data
Laura Thomas, David Kessler, John Campbell, Jill Morrison, Tim J Peters, Chris Williams, Glyn Lewis, Nicola Wiles
British Journal of General Practice 2013; 63 (617): e852-e858. DOI: 10.3399/bjgp13X675430
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Keywords

  • antidepressants
  • prevalence
  • primary health care
  • treatment resistant depression

More in this TOC Section

  • Academic performance of ethnic minority versus White doctors in the MRCGP assessment 2016-2021: cross sectional study
  • Diagnostic delays for breathlessness: a qualitative study in primary care to understand current care and inform future pathways
  • Physical activity for chronic back pain: qualitative interviews among patients and GPs
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