Age, years, mean (SD) | 71 (10) | 70 (11) | |
Age range, years | 36–105 | 37–99 | 0.070 |
Female sex, n (%) | 3056 (46) | 1100 (49) | 0.009 |
Body mass index, mean, kg/m2 (SD) | 27.04 (5.94) | 29.42 (6.69) | <0.001 |
Asthma co-diagnosis, n (%) | 878 (13) | 296 (13) | 0.900 |
Asthma ever diagnosed, n (%) | 2237 (33) | 821 (36) | 0.009 |
|
Smoking status | | | |
Never smoker, n (%) | 566 (8) | 315 (14) | <0.001 |
Ex-smoker, n (%) | 3731 (56) | 1209 (54) | 0.090 |
Current smoker, n (%) | 2255 (34) | 680 (30) | 0.002 |
No record of smoking status, n (%) | 150 (2) | 51 (2) | 0.700 |
|
Spirometry and COPD severity, | | | |
FEV1/FVC, mean (SD) | 0.55 (0.10) | 0.78 (0.07) | <0.001 |
FEV1, l, mean (SD) | 1.38 (0.60) | 1.76 (0.60) | <0.001 |
FEV1 % predicted, mean (SD) | 58 (18) | 72 (18) | <0.001 |
MRC breathlessness scale, % | | | |
1 | 12 | 12 | 0.070 |
2 | 41 | 42 | 0.070 |
3 | 29 | 30 | 0.070 |
4 | 15 | 14 | 0.070 |
5 | 3 | 2 | 0.070 |
Exacerbations, events/year, median (range) | 2.42 (0 to 25) | 2.43 (0 to 25) | 0.890 |
|
COPD clinical diagnostic code | | | |
COPD, n (%) | 3129 (46.7) | 1029 (45.6) | 0.400 |
Mild COPD, n (%) | 1095 (16.3) | 558 (24.7) | <0.001 |
Moderate COPD, n (%) | 1237 (18.5) | 325 (14.4) | <0.001 |
Severe COPD, n (%) | 509 (7.6) | 74 (3.3) | <0.001 |
Very severe COPD, n (%) | 76 (1.1) | 3 (0.1) | <0.001 |
COPD not otherwise specified, n (%) | 424 (6.3) | 128 (5.7) | 0.700 |
Bronchitis, n (%) | 56 (0.8) | 52 (2.3) | <0.001 |
Emphysema, n (%) | 176 (2.6) | 86 (3.8) | 0.004 |