Median age, years (IQR) | 2.39 (1.39–3.66) |
|
Sex, female | 54 379 (47.56) |
|
Seasonb | |
Winter | 41 830 (36.59) |
Spring | 30 110 (26.34) |
Summer | 15 108 (13.21) |
Autumn | 27 281 (23.86) |
|
RTI typec | |
URTI | 16 048 (14.04) |
LRTI | 68 634 (60.03) |
AOM | 28 604 (25.02) |
URTI and LRTI | 662 (0.58) |
Other mix | 381 (0.33) |
|
Comorbidity | 6625 (5.79) |
|
Antibiotic class | |
Cephalosporin | 847 (0.74) |
Macrolides | 11 571 (10.12) |
Broad-spectrum penicillin (amoxicillin, co-amoxiclav) | 87 723 (76.73) |
Penicillinase-resistant (flucloxacillin) | 275 (0.24) |
Penicillin V (phenoxymethylpenicillin) | 13 673 (11.96) |
Quinolones | 7 (0.01) |
Trimethoprim-cotrimoxazole | 233 (0.20) |
|
Vaccination status at index date (complete) | 43 401 (37.96) |
|
Vaccination status at end of study period (complete)d | 106 803 (93.42) |
|
Social deprivation quintilese | |
1 (least deprived) | 25 125 (21.99) |
2 | 23 021 (20.14) |
3 | 20 935 (18.32) |
4 | 23 186 (20.28) |
5 (most deprived) | 21 994 (19.24) |
Not linked to IMD | 68 (0.06) |
|
Previous response failuresf in last 12 months | |
None | 111 281 (97.33) |
1 | 3011 (2.63) |
2 | 37 (0.03) |
|
Median previous RTI consultations in last 12 months (IQR) | 4 (2–7) |
|
Number of children with an RTI-associated antibiotic prescription during the 12 months before the index antibiotic prescription (T0) | |
None | 95 383 (83.43) |
1 | 14 929 (13.06) |
≥2 | 4017 (3.51) |