Skip to main content

Main menu

  • HOME
  • ONLINE FIRST
  • CURRENT ISSUE
  • ALL ISSUES
  • AUTHORS & REVIEWERS
  • SUBSCRIBE
  • BJGP LIFE
  • MORE
    • About BJGP
    • Conference
    • Advertising
    • eLetters
    • Alerts
    • Video
    • Audio
    • Librarian information
    • Resilience
    • COVID-19 Clinical Solutions
  • RCGP
    • BJGP for RCGP members
    • BJGP Open
    • RCGP eLearning
    • InnovAIT Journal
    • Jobs and careers

User menu

  • Subscriptions
  • Alerts
  • Log in

Search

  • Advanced search
British Journal of General Practice
Intended for Healthcare Professionals
  • RCGP
    • BJGP for RCGP members
    • BJGP Open
    • RCGP eLearning
    • InnovAIT Journal
    • Jobs and careers
  • Subscriptions
  • Alerts
  • Log in
  • Follow bjgp on Twitter
  • Visit bjgp on Facebook
  • Blog
  • Listen to BJGP podcast
  • Subscribe BJGP on YouTube
Intended for Healthcare Professionals
British Journal of General Practice

Advanced Search

  • HOME
  • ONLINE FIRST
  • CURRENT ISSUE
  • ALL ISSUES
  • AUTHORS & REVIEWERS
  • SUBSCRIBE
  • BJGP LIFE
  • MORE
    • About BJGP
    • Conference
    • Advertising
    • eLetters
    • Alerts
    • Video
    • Audio
    • Librarian information
    • Resilience
    • COVID-19 Clinical Solutions
Oral Presentations

MULTIPAP Study: Improving healthcare for patients with multimorbidity

Alexandra Prados-Torres, Isabel del Cura-González, Juan Daniel Prados-Torres, Christiane Muth, Francisca Leiva-Fernández, Juan A Lopez-Rodriguez and Francisca González-Rubio
British Journal of General Practice 2020; 70 (suppl 1): bjgp20X711257. DOI: https://doi.org/10.3399/bjgp20X711257
Alexandra Prados-Torres
EpiChron Research Group on Chronic Diseases, Aragon Health Sciences Institute, Miguel Servet University Hospital, Zaragoza, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Isabel del Cura-González
Primary Care Research Unit, Gerencia de Atención Primaria. Department of Preventive Medicine and Public Health, University Rey Juan Carlos, Madrid, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Juan Daniel Prados-Torres
Multiprofesional Teaching Unit of Community and Family Atention ‘Distrito Atención Primaria Málaga-Guadalhorce’, Málaga, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Christiane Muth
Institute of General Practice, Johann Wolfgang Goethe University, Frankfurt/Main, Germany
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francisca Leiva-Fernández
Multiprofesional Teaching Unit of Community and Family Atention ‘Distrito Atención Primaria Málaga-Guadalhorce’, Andalusian Health Service, Málaga, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Juan A Lopez-Rodriguez
Primary Care Research Unit, Gerencia de Atención Primaria. Department of Preventive Medicine and Public Health, University Rey Juan Carlos, General Ricardos Primary Health Care Centre, Madrid, Spain
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Francisca González-Rubio
EpiChron Research Group on Chronic Diseases, Aragon Health Sciences Institute, Aragón; Miguel Servet University Hospital, Delicias-Sur Primary Care Health Centre, SALUD, Zaragoza, Spain.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Info
  • eLetters
Loading

Abstract

Background The steady rise in multimorbidity entails serious consequences for our populations, challenges healthcare systems, and calls for specific clinical approaches of proven effectiveness. The MULTIPAP Study comprises three sequential projects (MULTIPAP and MULTIPAP Plus RCTs, and the MULTIPAP Cohort). Results of MULTIPAP RCT are presented.

Aim To evaluate the effectiveness of a complex, patient-centred intervention in young-old patients with multimorbidity and polypharmacy.

Method Pragmatic cluster-randomised clinical trial in a primary healthcare setting. GPs were randomly allocated to either conventional care or the MULTIPAP intervention based on the Ariadne Principles with two components: GPs e-training (that is, eMULTIPAP addresses specific, key concepts on multimorbidity, polypharmacy and shared decision-making) and GP–patient-centred interview. Young-old patients aged 65–74 years with multimorbidity and polypharmacy were included. Main outcome: difference in the Medication Appropriateness Index (MAI) after 6-month follow-up between groups. Secondary outcomes: MAI, quality of life, patient perception, health services use, treatment adherence and cost-effectiveness after 12-month follow-up.

Results 117 GPs from 38 Spanish primary health care recruited 593 patients randomly assigned to the intervention/control groups. Difference in MAI scores between groups in the intention-to-treat analysis after 6 months’ follow-up: −2.42 (−4.27 to −0.59), P = 0.009 (adjusted difference in mean MAI score −1.81(−3.35 to −0.27), P = 0.021). Secondary outcomes: not significant, including quality of life (adjusted difference in mean EQ-5D-5L (VAS) 2.94 (−1.39 to 7.28), P = 0.183, EQ-5D-5L (index) −0.006(−0.034 to 0.022), P = 0.689).

Conclusion The intervention significantly improved medication appropriateness. The observed quality of life improvement was not significant. GPs e-training in multimorbidity has shown to be feasible and well accepted by the professionals. Future studies may test whether this format facilitates implementation.

  • © British Journal of General Practice 2020
Back to top
Previous ArticleNext Article

In this issue

British Journal of General Practice: 70 (suppl 1)
British Journal of General Practice
Vol. 70, Issue suppl 1
June 2020
  • Table of Contents
  • Index by author
Email Article

Thank you for recommending British Journal of General Practice.

NOTE: We only request your email address so that the person to whom you are recommending the page knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
MULTIPAP Study: Improving healthcare for patients with multimorbidity
(Your Name) has forwarded a page to you from British Journal of General Practice
(Your Name) thought you would like to see this page from British Journal of General Practice.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
MULTIPAP Study: Improving healthcare for patients with multimorbidity
Alexandra Prados-Torres, Isabel del Cura-González, Juan Daniel Prados-Torres, Christiane Muth, Francisca Leiva-Fernández, Juan A Lopez-Rodriguez, Francisca González-Rubio
British Journal of General Practice 2020; 70 (suppl 1): bjgp20X711257. DOI: 10.3399/bjgp20X711257

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
MULTIPAP Study: Improving healthcare for patients with multimorbidity
Alexandra Prados-Torres, Isabel del Cura-González, Juan Daniel Prados-Torres, Christiane Muth, Francisca Leiva-Fernández, Juan A Lopez-Rodriguez, Francisca González-Rubio
British Journal of General Practice 2020; 70 (suppl 1): bjgp20X711257. DOI: 10.3399/bjgp20X711257
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
  • Mendeley logo Mendeley

Jump to section

  • Top
  • Article
  • Info
  • eLetters

More in this TOC Section

  • Time for change? A comparative analysis of GPs’ opinions on appointment length
  • Motivating factors behind skill mix change: results from a practice managers’ survey in England
  • Emergency Admission Risk Prediction (EARP) tools in primary care to reduce emergency admissions to hospital: clash of evidence and practice
Show more Oral Presentations

Related Articles

Cited By...

Intended for Healthcare Professionals

BJGP Life

BJGP Open

 

Tweets by @BJGPjournal

 
 

British Journal of General Practice

NAVIGATE

  • Home
  • Current Issue
  • All Issues
  • Online First
  • Authors & reviewers

RCGP

  • BJGP for RCGP members
  • BJGP Open
  • RCGP eLearning
  • InnovAiT Journal
  • Jobs and careers

MY ACCOUNT

  • RCGP members' login
  • Subscriber login
  • Activate subscription
  • Terms and conditions

NEWS AND UPDATES

  • About BJGP
  • Alerts
  • RSS feeds
  • Facebook
  • Twitter

AUTHORS & REVIEWERS

  • Submit an article
  • Writing for BJGP: research
  • Writing for BJGP: other sections
  • BJGP editorial process & policies
  • BJGP ethical guidelines
  • Peer review for BJGP

CUSTOMER SERVICES

  • Advertising
  • Contact subscription agent
  • Copyright
  • Librarian information

CONTRIBUTE

  • BJGP Life
  • eLetters
  • Feedback

CONTACT US

BJGP Journal Office
RCGP
30 Euston Square
London NW1 2FB
Tel: +44 (0)20 3188 7400
Email: journal@rcgp.org.uk

British Journal of General Practice is an editorially-independent publication of the Royal College of General Practitioners
© 2023 British Journal of General Practice

Print ISSN: 0960-1643
Online ISSN: 1478-5242