Intra-articular and soft-tissue corticosteroid injection (CSI) is a common treatment for orthopaedic conditions, often performed in primary care. CSIs are believed to have a low incidence of minor local side effects, and no known association with acute ischaemic cardiac events. This study suggests an increased incidence of acute coronary syndrome (ACS) in the week following CSI. The possible association of a common treatment and a life-threatening side effect is of importance to patients, clinicians, and policymakers. |