Age, years, mean (SD) | | 69.8 (9.6) | 0 (0.0) |
|
Sex | Female | 394 (52.9) | 3 (0.4) |
Male | 348 (46.7) | |
|
Ethnicity | White | 719 (96.5) | 0 (0.0) |
Mixed ethnicity | 6 (0.8) | |
Asian | 10 (1.3) | |
Black | 5 (0.7) | |
Other | 5 (0.7) | |
|
Comorbidities in GP recordb | Hypertension | 429 (57.6) | n/a |
Chronic kidney disease | 204 (27.4) | |
Diabetes | 164 (22.0) | |
History of urinary tract infection | 122 (16.4) | |
Cancer | 112 (15.0) | |
Thyroid disease | 89 (11.9) | |
Prostate disorders | 85 (11.4) | |
Ischaemic heart disease | 82 (11.0) | |
Atrial fibrillation | 54 (7.2) | |
Myocardial infarction | 44 (5.9) | |
Kidney stones | 40 (5.4) | |
Transient ischaemic attack | 28 (3.8) | |
Stroke | 19 (2.6) | |
Heart failure | 15 (2.0) | |
Peripheral vascular disease | 14 (1.9) | |
|
Smoking status | Never smoked | 386 (51.8) | 2 (0.3) |
Former smoker | 327 (43.9) | |
Current smoker | 30 (4.0) | |
|
Biochemical markers at visit 1, mean (SD) | Serum creatinine (µmol/l) | 88.4 (23.2) | 16 (2.1) |
Serum cystatin C (mg/l) | 1.2 (0.4) | 83 (11.1) |
ACR (mg/mmol) | 3.4 (9.4)c | 51 (6.8) |
eGFR-serum creatinine (ml/min/1.73 m2) | 69.4 (16.2) | 19 (2.6) |
eGFR-serum cystatin C (ml/min/1.73 m2) | 61.9 (20.3) | 86 (11.5) |
|
eGFR over the extended baseline, mean (SD) | eGFR-serum creatinine (ml/min/1.73 m2) | 68.9 (15.5) | 6 (0.8) |
eGFR-serum cystatin C (ml/min/1.73 m2) | 61.1 (19.4) | 8 (1.1) |