RT Journal Article SR Electronic T1 Costs of antidepressant overdose: a preliminary study. JF British Journal of General Practice JO Br J Gen Pract FD British Journal of General Practice SP 733 OP 734 VO 49 IS 446 A1 N Kapur A1 A House A1 F Creed A1 E Feldman A1 T Friedman A1 E Guthrie YR 1999 UL http://bjgp.org/content/49/446/733.abstract AB There is ongoing debate regarding the relative cost effectiveness of different classes of antidepressants. Although factors such as tolerability and discontinuation rates have been taken into account, there has been little consideration of the cost of overdose. In the current study we examined the cost of antidepressant overdose at four teaching hospitals over a four-week period and found that the cost of selective serotonin reuptake inhibitor overdose was less than half that of tricyclic anti-depressant overdose. The cost of overdose is often ignored and should be considered in future analyses of the cost effectiveness of different antidepressant prescribing policies in primary care.