PT  - JOURNAL ARTICLE
AU  - Colin J Greaves
AU  - Andrew Middlebrooke
AU  - Lucy O'Loughlin
AU  - Sandra Holland
AU  - Jane Piper
AU  - Anna Steele
AU  - Tracy Gale
AU  - Fenella Hammerton
AU  - Mark Daly
TI  - Motivational interviewing for modifying diabetes risk: a randomised controlled trial
AID  - 10.3399/bjgp08X319648
DP  - 2008 Aug 01
TA  - British Journal of General Practice
PG  - 535--540
VI  - 58
IP  - 553
4099  - http://bjgp.org/content/58/553/535.short
4100  - http://bjgp.org/content/58/553/535.full
SO  - Br J Gen Pract2008 Aug 01; 58
AB  - Background Around 10–15% of adults aged over 40 years have pre-diabetes, which carries a high risk of progression to type 2 diabetes. Intensive lifestyle intervention reduces progression by as much as 58%. However, the cost and personnel requirements of these interventions are major obstacles to delivery in NHS primary care.Aim To assess the effectiveness of a low-cost intervention, delivered in primary care by non-NHS staff, to reduce the risk of diabetes through weight loss and physical activity.Design of study Pragmatic single-blind randomised controlled trial with researchers and statistician blinded to group allocation.Setting UK primary care.Method One-hundred and forty-one participants with a body mass index of 28 kg/m2 or more, but without diabetes or heart disease, received either information leaflets or individual behavioural counselling using motivational interviewing techniques. The intervention was delivered by five counsellors recruited from the local community. The primary outcomes were the proportions of participants meeting predefined targets for weight loss (5%) and moderate physical activity (150 minutes/week) after 6 months.Results Using intention-to-treat analysis, more people in the intervention group achieved the weight-loss target (24% versus 7% for controls; odds ratio [OR] = 3.96; 95% confidence interval [Cl] = 1.4 to 11.4; number needed to treat [NNT] = 6.1 (95% Cl = 4 to 21). The proportion achieving the physical activity target did not increase significantly (38% versus 28% for controls; OR = 1.6; 95% Cl = 0.7 to 3.8).Conclusion Short-term weight loss, at a level which, if sustained, is clinically meaningful for reducing diabetes risk, is achievable in primary care, without excessive use of NHS monetary or personnel resources.