PT  - JOURNAL ARTICLE
AU  - Barclay M Goudie
AU  - Peter T Donnan
AU  - Geraldine Fairfield
AU  - Sally S Al-Agilly
AU  - Philip G Cachia
TI  - Dependency rather than old age increases the risk of warfarin-related bleeding
DP  - 2004 Sep 01
TA  - British Journal of General Practice
PG  - 690--692
VI  - 54
IP  - 506
4099  - http://bjgp.org/content/54/506/690.short
4100  - http://bjgp.org/content/54/506/690.full
SO  - Br J Gen Pract2004 Sep 01; 54
AB  - There is uncertainty about the safety of anticoagulation with warfarin in the elderly. This cohort study investigated the risk factors for warfarin-related bleeding in a primary care setting. In multiple regression analyses increased risk of bleeding was associated with domiciliary monitoring of international normalised ratio (INR), low proportion of INR tests in the target range, high intensity of anticoagulation, and male sex. Age was not associated with increased risk after adjustment. High levels of dependency, not old age, should raise concerns about the safety of anticoagulation with warfarin.