TY - JOUR T1 - From the journals, March–April 2006 JF - British Journal of General Practice JO - Br J Gen Pract SP - 383 LP - 383 VL - 56 IS - 526 AU - Richard Lehman Y1 - 2006/05/01 UR - http://bjgp.org/content/56/526/383.abstract N2 - 1001 A cure for most people with chronic hepatitis B infection — entecavir, a distinct advance on lamivudine.1021 Don't be too surprised if thalidomide appears on the treatment list of a myeloma patient — it prolongs survival if given at the start of treatment, and works well in the elderly (Lancet page 825), but has a lot of side-effects.1130 Patients over 70 who are taking antidepressants have a 68% chance of getting depressed again if they stop, reduced to 37% if they carry on. Continued psychotherapy makes no difference.1157 A good review of acute confusional states (delirium) in the elderly. They can resolve completely with treatment of the cause, or mark a steep decline in a dementing process.1231 An important pragmatic study from the STAR*D series shows that a third of patients who don't respond to one serotonin reuptake inhibitor (SRI) antidepressant will … ER -