@article {Bartholomeeusen497, author = {Stefaan Bartholomeeusen and Jan Vandenbroucke and Carla Truyers and Frank Buntinx}, title = {Time trends in the incidence of peptic ulcers and oesophagitis between 1994 and 2003}, volume = {57}, number = {539}, pages = {497--499}, year = {2007}, publisher = {Royal College of General Practitioners}, abstract = {This study examined time trends in the incidence of peptic ulcers and oesophagitis, and the prescription of acid-inhibiting drugs in the period 1994{\textendash}2003. Data were retrieved from records in general practices in Flanders, Belgium. The incidence of duodenal ulcers decreased by two-thirds and the incidence of gastric ulcers halved, the incidence of oesophagitis initially increased and decreased slowly later on. In 10 years the proportion of patients taking proton-pump inhibitors rose sixfold while the proportion taking H2 antagonists remained stable.}, issn = {0960-1643}, URL = {https://bjgp.org/content/57/539/497}, eprint = {https://bjgp.org/content/57/539/497.full.pdf}, journal = {British Journal of General Practice} }